library(PALMO)
#> Loading required package: gridPALMO
(Platform for Analyzing Longitudinal Multi-omics data) is a
platform for anayzing longitudinal data from bulk as well as single
cell. It allows to identify inter-, intra-donor variations in genes over
longitudinal time points. The analysis can be done on bulk expression
dataset without known celltype information or single cell with
celltype/user-defined groups. It allows to infer stable and variable
features in given donor and each celltype (or user defined group). The
outlier analysis can be performed to identify technical/biological
perturbed samples in donor/participant. Further, differential analysis
can be performed to decipher time-wise changes in gene expression in a
celltype.