xlink: Genetic Association Models for X-Chromosome SNPS on Continuous, Binary and Survival Outcomes

The expression of X-chromosome undergoes three possible biological processes: X-chromosome inactivation (XCI), escape of the X-chromosome inactivation (XCI-E),and skewed X-chromosome inactivation (XCI-S). To analyze the X-linked genetic association for phenotype such as continuous, binary, and time-to-event outcomes with the actual process unknown, we propose a unified approach of maximizing the likelihood or partial likelihood over all of the potential biological processes. The methods are described in Wei Xu, Meiling Hao (2017) <doi:10.1002/gepi.22097>. And also see Dongxiao Han, Meiling Hao, Lianqiang Qu, Wei Xu (2019) <doi:10.1177/0962280219859037>.

Version: 1.0.1
Depends: R (≥ 3.1.0)
Imports: survival (≥ 2.41.3)
Suggests: knitr, rmarkdown, testthat
Published: 2019-08-20
DOI: 10.32614/CRAN.package.xlink
Author: Wei Xu [aut], Meiling Hao [aut], Yi Zhu [cre]
Maintainer: Yi Zhu <yizhu87 at gmail.com>
BugReports: https://github.com/qiuanzhu/xlink/issues
License: GPL-2
URL: https://github.com/qiuanzhu/xlink
NeedsCompilation: no
Materials: NEWS
CRAN checks: xlink results


Reference manual: xlink.pdf
Vignettes: An Introduction to xlink


Package source: xlink_1.0.1.tar.gz
Windows binaries: r-devel: xlink_1.0.1.zip, r-release: xlink_1.0.1.zip, r-oldrel: xlink_1.0.1.zip
macOS binaries: r-release (arm64): xlink_1.0.1.tgz, r-oldrel (arm64): xlink_1.0.1.tgz, r-release (x86_64): xlink_1.0.1.tgz, r-oldrel (x86_64): xlink_1.0.1.tgz
Old sources: xlink archive


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